Mental health articles
OF mental health care and mentally ill
antipsychotics
antipsychotics side effects chart
Unfortunately, antipsychotics may have some unwanted side effects which must be weighed against their benefits. Sometimes, soon after someone starts the medicine, the person may develop a tremor of their fingers, dribble saliva and find it difficult to move because they feel rigid. These symptoms are similar to those experienced by people who have Parkinson’s […]
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Typical antipsychotics ：Evidence of effectiveness
Typical antipsychotics ：Evidence of effectiveness There is now more than 50 years of clinical experience treating psychosis with typical antipsychotics and an equivalent quantity of research. Typical antipsychotics are all equally effective at treating the positive symptoms of psychosis and overall approximately 80% of people will respond to treatment. Detailed summaries of the effi cacy […]
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Side effects of antipsychotics
Side effects Typical antipsychotics are sometimes classified, in the British National Formulary for example, by their side-effect profi le. This is dependent on their propensity to act not only as an antagonist at dopamine D2 receptors but at other dopamine receptors and other types of receptors such as alpha-1 adrenaline, H1 histamine and M1 acetylcholine […]
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antipsychotics medication
Antipsychotic medication, as the name implies, is used to treat symptoms of psychosis. Antipsychotics were also known as neuroleptics and in times past were referred to, somewhat misleadingly, as major tranquilisers. Chlorpromazine, the fi rst of the antipsychotics, was introduced in 1952 and was the fi rst effective treatment for psychosis. The impact of this […]
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Typical antipsychotics mechanism of action
Typical antipsychotics Mechanism of action Extensive research was undertaken into the mechanisms of action of typical antipsychotics. This has led to the development of a range of theories regarding the pathology of psychosis. Over time, it became clear that it was the ability to act as a dopamine antagonist that produced the clinically desirable effect, […]
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Atypical antipsychotics mechanism of action
Atypical antipsychotics The term ‘atypical’ is applied to the second generation of antipsychotics owing to their reduced propensity to cause EPSEs. The fi rst of this group was clozapine, which was fi rst synthesised in 1958. After initial launch in the 1970s it was withdrawn because of the recognition of previously unidentifi ed and potentially […]
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