Mental health articles

OF mental health care and mentally ill

Typical antipsychotics mechanism of action

Typical antipsychotics Mechanism of action  Extensive research was undertaken into the mechanisms of action of typical antipsychotics. This has led to the development of a range of theories regarding the pathology of psychosis. Over time, it became clear that it was the ability to act as a dopamine antagonist that produced the clinically desirable effect, […]

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Atypical antipsychotics mechanism of action

Atypical antipsychotics The term ‘atypical’ is applied to the second generation of antipsychotics owing to their reduced propensity to cause EPSEs. The fi rst of this group was clozapine, which was fi rst synthesised in 1958. After initial launch in the 1970s it was withdrawn because of the recognition of previously unidentifi ed and potentially […]

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Dopaminergic side effects

Dopaminergic side effects While dopamine D2 blockade in the meso-limbic pathway produces the desired symptom relief, three other pathways, the meso-cortical, nigro-striatal and tuberoinfundibular, all use D2 receptors and are also blockaded. This leads to a series of side effects dependent on the function of each pathway. Meso-cortical blockade has been implicated in the exacerbation […]

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Somatizing in children and adolescents

Most professionals accept the need to take a holistic approach bringing together the physical and psychological dimensions in the assessment and treatment of children and adolescents. Complaints of somatic symptoms are common in children presenting with psychological problems. This chapter deals more specifically with conditions in which the main complaints are of somatic symptoms and […]

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Eating disorders in children and adolescents

Eating disorders are conditions in which there is excessive preoccupation and concern with control of body weight and shape, with grossly restricted food intake. The term ‘eating disorder’ in children and adolescents covers a range of early onset conditions where one or all of the psychological, social and physical areas of functioning is involved. The […]

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Factors associated with poor prognosis in anorexia nervosa

  The chance of relapse or a poorer outcome is based on the following factors, which include: −Age of onset (younger do better) +Duration of illness +Severity of weight loss +Hyperactivity, vomiting +Bulimia and purging +Obsessive-compulsive symptoms −Hysterical personality +Difficulty with weight gain in the ward environment/short duration inpatient treatment −Ability to get weight into […]

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Treatment efficacy: generalized anxiety disorder

Treatment efficacy: generalized anxiety disorder The NHS Centre for Reviews and Dissemination’s meta-analysis of the comparative efficacy of treatments for generalized anxiety disorder (2002e) found that both CBT and pharmacotherapy (predominantly drugs classed as benzodiazepines) are ‘effective treatments for GAD and that both yielded relatively large effect sizes on measures of anxiety severity at posttreatment’. […]

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Principles and practice of cognitive behaviour therapy

The cognitive theories and treatments in use today have generally followed on from Beck’s original theories. Broadly speaking, cognitive approaches to emotional disorders focus on two main areas of a person’s experience; the appraisals a person makes while in a situation, and the information processing biases that occur. In anxiety, appraisals that are made generally […]

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Body Dysmorphic Disorder Stories

Case study: body dysmorphic disorder Susan is a 33-year-old hairdresser who attended her GP following a recent bout of ill-health involving panic attacks, low mood, attempted suicide and avoidance of leaving the house. The problem began six weeks earlier when she developed a light rash (which she called spots) over her neck area. She believed […]

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Diagnosis Criteria for Anorexia Nervosa

Criteria for diagnosis of anorexia nervosa Current classification and definition (the main points of ICD1O (WHO 1992) and DSM-IV (APA 1994) combined) body weight at least 15 per cent below that for normal/expected age and height: in children this is weight below the second percentile; weight loss is self-induced; self-perception of being too fat; absence […]

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